Kintor Announces New Advanced Androgen Receptor Drug GT20029

China Trial Enrolls 180 Patients To Complete Enrollment (8/22/23)

On August 22, 2023, Kintor Pharmaceutical announced the completion of patient enrollment in a phase 2 trial in China for GT20029. This means all of the patients needed to complete the study have been enrolled, and will undergo their dosing schedule over the next 12 weeks. The trial of GT20029, which is an androgen receptor degrader drug, is a multi-center, randomized, double-blind, placebo-controlled study designed to evaluate the efficacy and safety of GT20029 in treating male AGA, and to determine the recommended dosage for the phase 3 clinical trial.

Dr. Youzhi Tong, CEO of Kintor Pharmaceutical, said “We expect to release the top-line data of the Phase II clinical trial in the first quarter of 2024, and look forward to collecting more efficacy and safety data of GT20029 in this trial.

US GT20029 Trial Begins: Update (2/3/22)

Steady and exciting progress continues for Kintor Pharmaceutical. Early this morning, apress releasewas issued by Kintor announcing the dosing of the first subject in a phase 1 clinical trial for its innovative drug GT20029. See below for description of GT20029. The drug will be delivered in a topical gel form and is being trialed against androgenetic alopecia and acne vulgaris. Dr. Youzhi Tong, CEO of Kintor Pharma, shared these words in the release: “The start of this US clinical trial represents a significant milestone for Kintor, as it demonstrates the beginning of the international development of the company’s fourth innovative drug. In preclinical studies, we found that GT20029 can effectively block the androgen receptor pathway and its physiological function by degrading the AR protein. By limiting skin penetration, GT20029 inhibits local androgenic effects in peripheral skin tissues and so achieve good safety.

Bonus news: AClinicalTrials.govpage for a US phase 2 trial of Kintor’s other drug pyrilutamide has just been published. It appears that the trial is set to begin immediately. Three cohorts will test a 2.5 dose, a 5mg once and twice daily.

FDA Grants IND For Advanced GT20029 PROTAC Drug: Update (7/13/21)

Kintor is on a roll. Just days after we received the update that the FDA approved a phase 2 study of pyrilutamide in the US, we now get news that Kintor has also received an IND for their new potential breakthrough drug GT20029. Even better, thepress releasestates that Kintor received approval for a phase 1 trial of GT20029 in China back in April 2021 and the first patient dosing is expected in July 2021! To review the many theorized advantages of GT20029, which is a PROTAC drug, see the article below.

There is no set date for the US trial of GT20029 at this time, but according to today’s release,Kintor has plans to complete “a randomised, double-blind, vehicle-controlled, parallel-group, dose escalation study to evaluate the safety, tolerability and pharmacokinetics of GT20029 following topical single and multiple ascending dose administration.

Original Article

中国Kintor制药宣布a press release today that the company is bringing yet another androgen receptor-based drug into clinical trials for the treatment of androgenic alopecia.

Androgen Receptor Degrader GT20029

Those who have been following along over the past year must be familiar withpyrilutamide, a topical androgen receptor-antagonist drug which is being trialed by Kintor in China and the USA for pattern hair loss. Pyrilutamide entered into a phase 2 trial in China at the end of 2020 and completed a phase 1 trial in USA last year for androgenic alopecia. The program is quite ambitious as Kintor has formally announced their plans to enter a phase 3 trial for pyrilutamide for AGA by the end of 2021, but it appears they’re not done yet either.

On February 2, 2021, Kintor announced that an investigational new drug application (IND) for the drug GT20029 has been approved by the NMPA of China (equivalent to the FDA) for the indications of androgenic alopecia and acne vulgaris. GT20029 is a new advanced form of an anti-androgen called a PROTAC which stands for proteolysis targeting chimera. It will be developed alongside pyrilutamide in the company’s pipeline.

Click To Enlarge -

A simpledefinitionof a PROTAC: “a heterobifunctional small molecule composed of two active domains and a linker capable of removing specific unwanted proteins.” Kintor states that GT20029 was developed through the company’s in-house PROTAC platform. Here are some explanatory statements by Kintor in their latestpress release:

“GT20029 is an AR degrader that degrades the AR protein. The mechanism of action of GT20029is to recruit the AR protein to the E3 ubiquitin ligase for degradation. It acts on the local tissues ofthe peripheral skin and local hair follicle sebaceous glands, which reduces the sensitivity of AR toandrogens without systemic exposure to the drug.

“As each PROTAC molecule can degrade multiple AR proteins, drugs based on PROTAC can achieve efficacy with a low dosage. In addition, as long as there are a small amount of PROTAC molecules in the cells, the efficacy of the drugs can be maintained, which can significantly reduce the dosing frequency as compared to other small molecule drugs.”

“According to animal experiments, the efficacy of GT20029 is superior to other small molecule AR inhibitors. In addition, GT20029 will not cause excessive drug accumulation and notable side effects. While achieving efficacy, GT20029 can effectively avoid systemic exposure to mitigate or avoid the side effects of the oral androgen signaling pathway inhibitors.”

Sounds good, yeah? This is the kind of drug evolution that most of us have been hoping for since finasteride became mainstream decades ago. It sounds like Kintor is getting closer to the ideal anti-androgen for hair regrowth and hair loss prevention (if all goes well). Kintor also states that they believe GT20029 is the first topical PROTAC drug which has entered the clinical trial stage anywhere in the world. An IND is expected to be filed soon in the USA for GT20029 as well.

What does everyone think of Kintor’s progress and efforts to create new innovative drugs for preserving hair growth? Comment below.


  1. 英格兰vs美国皇冠比分 在February 1, 2021 at 8:43 pm

    I’m digging Kintor’s efforts here and the fact that the company is China based is a plus for me, too. Chinese companies tend to be serious about their science and their business for sure. This new drug may be a bit down the line, but do not forget about pyrilutamide which is intended to reach phase 3 this year! Hats off to Kintor Pharmaceuticals (Pun fully intended).
    Feb 1, 2021 at 20:42

    • Yoda 在February 2, 2021 at 6:04 pm

      Thanks Admin! As far as Chinese companies, possibly more serious about their business and there’s less regulation but I wouldn’t bet on them being superior in science. Although you said “serious” so maybe that wasn’t what you were saying. Keep up the good work!

    • John Taylor 在February 8, 2021 at 2:00 pm

      Hello Admin, great work as always! I have followed the news regarding Nanofibers filled with minoxidil sulfate and wondered if you have any thoughts on this develpment.

    • Álvaro on July 30, 2021 at 8:19 am

      Finally!! a new compound in clinical trials! Hopefully it is more effective than finasteride and dutasteride, which although effective, do not eliminate the genetic burden of androgenic alopecia. Hopefully this compound is effective, especially for those of us who want to maintain our hair over the years, without having to go through more hair grafting operations. Thanks for your work Joseph !!

    • Chris 在February 5, 2022 at 7:57 pm


      I recently stumbled onto your blog. I appreciate the hard work you do! I’m new to this hair loss treatment scene and was wondering if you have a personal prediction of when there will be another effective treatment alternative to finasteride for hair loss? Unfortunately as an athlete I’m worried about the effects of nuking my DHT on my performance. I know you can’t know for sure, but if anyone would have a good prediction I would assume you would know best.

      Cheers from Vancouver.

      • 英格兰vs美国皇冠比分 在February 5, 2022 at 11:13 pm

        Thanks Chris. Please read the Ultimate Guide article and scroll through all of the recent articles. An effective alternative to finasteride could come in the form of pyrilutamide or the drug which is highlighted in this very article, GT20029. Maybe 2024-2027 for the both of them, starting in China.

    • Degraded 在February 8, 2022 at 8:48 pm

      你知道如果小型化毛囊仍然h吗世界杯球赛直播时间表20222022世界杯附加赛预测ave androgen receptors? Could this product reverse miniaturization if the receptors are “stuck on”? I’m wondering if increased sensitivity to androgen gets to the point where the receptor is just stuck on, which means a degrader could really help.

      • 英格兰vs美国皇冠比分 在February 9, 2022 at 8:52 am

        Yes miniaturized follicles still have androgen receptors. AR’s are a natural part of a hair follicle, they are essentially a protein. GT20029 could potentially reverse miniaturization if it can remove androgens from the hair follicles.

    • Sonia Ianni Ponquio 在February 25, 2022 at 10:43 am

      Bom dia amigos,tenho acompanhado algumas notícias desde 2018 sobre alopecia androgenetica, q causa dores na alma!!!!estou na expectativa dessa nova luz, GT20029!!!aguardo ansiosamente mais notícias!!!

      • Sonia Ianni Ponquio 在February 25, 2022 at 10:47 am

        Desculpem o erro de digitação, estou esperando notícias desde *2018* não desde 2088 ,impossível kkkkkk

  2. Anthony Salazar 在February 1, 2021 at 8:47 pm

    100% of my hopes for a legit treatment in the next 5 years lie with this company.

    • 英格兰vs美国皇冠比分 在February 1, 2021 at 8:47 pm

      Let’s go Anthony

    • Shayak 在February 1, 2021 at 11:42 pm

      Very very good news,i think the gods are also facing AGA these days that’s why all these miracle cures(probably).I just hope that the drug proves its efficacy and safety profile in the clinical trial and give all AGA sufferers releif.But the androgen enigma still continues,the same hormone which helped vellus hair become terminal in our childhood takes away all our hairs after puberty, uhhh nature!

  3. GG 在February 2, 2021 at 12:40 am

    hey guys,

    I am very new in this community and trying to catch up. The first big question on which I’d love to get a realistic response is that how long will it to have smth which really cures baldness (from NW7 to NW1). And what kind of treatments we may face in the forthcoming future for hair loss?
    Thanks in advance.

    • 英格兰vs美国皇冠比分 在February 4, 2021 at 8:59 pm

      GG, I would say you’re likely looking at 5-? years before something comes out that can restore a NW7 to NW1. The upcoming treatments include hair follicle cloning, gene editing, anti-androgens, and DP cell injections.

      • GG 在February 4, 2021 at 11:13 pm

        Thanks admin ❤️ I really appreciate ??
        5 years? That’s pretty soon. Why people get down about this matter anymore then ???♂️ the cure happened to be at the doorstep.
        Wish you all full head of hear ??

        • 英格兰vs美国皇冠比分 在February 5, 2021 at 9:03 am

          没有问题。5年是有可能的,因为日本的not guaranteed though, hope you can understand that part. One of the companies like TissUse or a Tsuji venture needs to enter a trial.

      • Augusto 在February 5, 2021 at 7:37 am

        Hello administrator! Samumed is also 5 years away? thanks for all your work

        • 英格兰vs美国皇冠比分 在February 5, 2021 at 9:04 am

          Samumed is about 12-14 months away (or less) pending results.

          • Atalan on August 23, 2023 at 10:21 pm

            Wait, does Biosplice / Samumed have something besides the dalosirvat they gave up on in 2022?

            • 英格兰vs美国皇冠比分 on August 24, 2023 at 8:59 pm

              No, my comment was dated February 2021.

  4. Fgsfds 在February 2, 2021 at 1:52 am

    Can anyone find the chemical structure? Or patent?

  5. DEE 在February 2, 2021 at 2:39 am

    任何这样的发展只能是积极的他re’s hoping it will bear fruition thanks admin for your research

  6. Diffuse Dude 在February 2, 2021 at 4:09 am

    God Please ? Plz Plz Plz Let this nightmare be done with once and for all ???

  7. Cody 在February 2, 2021 at 5:46 am

    After first hand nasty experience with anti androgens, anything labeled AA scares me. They claim no systemic side effects but it’s just hard to believe. Who knows. The aa did work for me for decades and then the side effects came crashing down hard.

    • Shayak 在February 2, 2021 at 7:40 am

      Which AA?

    • Josh 在February 4, 2022 at 12:59 pm

      Cody—interesting Cody. Which AA did you take and what were your sides? Have you done any blood work and rules out any psychosocial factors? Thanks. Fluridil has been great for me as a mild anti androgen. It has given me 0 sides and seems to maintain my hair. It’s binding affinity is also decent and better than breezula for Instance. Have you considered that?

  8. Steve 在February 2, 2021 at 5:57 am

    Aside from maybe Samumed, I fully believe the next product available for treatment of hairloss will come from this company. I wish them all the best of luck and hope they make those billions on their treatments, while companies in Europe and US sleep and delay their trials. they deserve to be left in the dust.

  9. Dale 在February 2, 2021 at 6:17 am

    嘿,GG,我认为没有人知道答案your first question. There are many promising treatments, but then again so it has been since I can remember (and surely you know that treatments are only one of two main ways to address this issue?) That said, what we read on this page is exciting compared to what we usually see.

    • GG 在February 2, 2021 at 6:30 am

      I totally agree Dale. I guess, if you are gonna be bald you have to just deal with that. I remember how my relative hoped in the beginning of 21st century that soon baldness would be cured. Two decades passed and I hear the same. It’s funny though that we are planning to go to Mars and on the Earth we have baldness problem. LOL.
      thanks for your reply.

      p.s. I am not trying to discourage anyone here <3. This is only my opinion

      • Afshin 在February 3, 2021 at 12:39 am

        You’re right ?

      • PP 在February 7, 2021 at 7:59 am

        Hi Admin,

        A big fan of your page and thanks again for all your hard work. I just wanted to ask what you think about PRP treatment for hair loss? It’s something I was hoping to undertake but I just wanted to get your opinion on it’s efficacy as a treatment on its own as I’m hoping to keep my existing hair and then wait for one of these other treatments to come through.

        • 英格兰vs美国皇冠比分 在February 7, 2021 at 10:09 am

          Hey PP, PRP is a ‘hit or miss’ type of treatment. It works decent for some and not for others. If money is no object to you it is definitely worth considering. I’ve heard recently from a scientist who works on PRP a lot that he believes it needs to be administered monthly for a bout 4 months in a row to be most effective, just a thought.

      • Josh 在February 4, 2022 at 1:06 pm

        GG—you are not discouraging others, but these comments are extremely unhelpful. I’ve mentioned this before to others, but Il keep going at it: judge updates on it’s merits and on the science. Don’t use fallacies like the argumentum ad antiquitatem to paint a dark picture of the future. Many things that seem simple are big issues in science. Hair loss is a very complex hormonal issue and the workings of the endocrine system isn’t well understood.

    • Josh 在February 4, 2022 at 1:01 pm

      Dale—I wonder which ones you are talking about? I’ve been following this for nearly a decade but 2021-2022 has been most promising so far.

      • Mezan 在February 21, 2022 at 4:59 am

        Yh the 20s really do look promising for us. But it seems like now there are more man balding than ever, and we also care a lot more about our hair now.

  10. ravensare 在February 2, 2021 at 6:39 am

    管理…我有一个question for you: what is your nationality?? american?? french??? thanks.

    • 英格兰vs美国皇冠比分 在February 2, 2021 at 9:40 am

      I’m American.

  11. Hope 在February 2, 2021 at 7:09 am

    Yay sounds like we have some real treatment coming our way!
    I have faith that this one will be effective without all the nasty side effects. Thanks admin!

  12. D1 在February 2, 2021 at 8:17 am

    @FollicleThought do you have much else in pipeline of news?

    • 英格兰vs美国皇冠比分 在February 2, 2021 at 9:44 am

      A few potential leads D1, hopefully another article or meaningful update soon.

  13. Balding Mark 在February 2, 2021 at 9:07 am

    Sounds Great but I guess the earliest we would get a product from Kintor is around 2023. Are there any news about Samumed (sorry if I spelled it wrong). Hope it will be released within this year!

    • 英格兰vs美国皇冠比分 在February 2, 2021 at 9:42 am

      Will check in on Samumed shortly, thanks.

  14. 英格兰vs美国皇冠比分 在February 2, 2021 at 9:43 am

    Also, don’t forget to check out the//, Follicum had a brief update yesterday as well.

  15. Devit 在February 2, 2021 at 10:28 am

    Hello Admin,

    In article I see this statement:
    “as long as there are a small amount of PROTAC molecules in the cells, the efficacy of the drugs can be maintained,”

    Does it mean we don’t have to apply daily?

    • 英格兰vs美国皇冠比分 在February 4, 2021 at 8:56 pm

      It’s highly likely that it does not need to be applied daily in theory, Devit.

  16. si 在February 2, 2021 at 10:30 am

    Hope I’m wrong but according to the article this seems more in step with medications to prevent hair loss like minoxidil then an agent to regrow hair. In other words dont bother with this guys its not for us.

    • 英格兰vs美国皇冠比分 在February 4, 2021 at 8:55 pm

      If you’ve ever studied finasteride results you’d notice that it sometimes regrows good amounts of hair.

  17. Andrew 在February 2, 2021 at 1:05 pm

    This is by far the best hair loss blog. Thanks for all your hard work for actually reaching out to companies and getting the scoop!

    • 英格兰vs美国皇冠比分 在February 2, 2021 at 7:12 pm

      I appreciate those kind words Andrew!

  18. Balding Mark 在February 2, 2021 at 2:31 pm

    Yes Admin thanks for all the hard work you put in for us! If there was one person who deserves to get a cure it’s you! I believe one day we will be there

    • 英格兰vs美国皇冠比分 在February 2, 2021 at 7:14 pm

      And I really appreciate those kind words Mark! Thank you!

  19. Terri 在February 3, 2021 at 8:47 am

    Thank you so much for all your work. I agree with “Balding Mark”, you deserve to be one of the first in line for whatever best serves those of us with this issue. All the best to you.

    • 英格兰vs美国皇冠比分 在February 4, 2021 at 8:55 pm

      Thank you Terri

  20. leon 在February 3, 2021 at 4:17 pm

    Hi Admin, do you think this is the year we‘ll finally see if SHT is a serious treatment if not even a cure? My gut feeling still says it will be the next treatment, with the most impact.

    • 英格兰vs美国皇冠比分 在February 4, 2021 at 8:54 pm

      I’m not sure Leon. There are steps that need to be made to get the trial going. I wish it would go into trials ASAP. I will provide an update whenever news is available of course.

  21. Sonic 2021年2月4日,凌晨4:56

    Thank you admin for this great update, really appreciate all you do and for always being the first source to update us. This website really is the best on the internet for hair loss.

    I’m really excited about this one. Hopefully this treatment follows the same pace as pyrilutamide and flies through all the trials

  22. Ben 在February 4, 2021 at 5:04 pm

    Hi Admin, have you been able to participate in the Stemson-stream?

    I couldn’t make it in time. Or user „Vienna“ maybe?

    Would be great to get a summary.

    • 英格兰vs美国皇冠比分 在February 4, 2021 at 6:31 pm

      Hi Ben, I tried to attend the Fortunis webinar, however, I was not given a link by the company.

  23. Shayak 在February 5, 2021 at 8:09 am

    你好管理员,do you know about any company researching on genetic therapies for hair loss, apart from moogene and exicure?

    • 英格兰vs美国皇冠比分 在February 5, 2021 at 9:08 am

      Not at the moment Shayak.

  24. Shayak 在February 5, 2021 at 9:19 am

    Okay,thank you for your response admin.

  25. Ahmed bekeer 在February 5, 2021 at 9:42 am

    I really like Dr. Ralf Paus is passionate about hair loss research and is happy to enter Germany in the field of hair loss treatment. I hope you are interested in Dr. Ralf Paus treatment of baldness and hair loss

  26. Woofy97 在February 5, 2021 at 5:39 pm

    I’m ready for a jaw dropping update. You know?

    • 英格兰vs美国皇冠比分 在February 5, 2021 at 6:54 pm

      I agree Woofy.

      • Devit 在February 6, 2021 at 9:43 am

        Is there something interesting to come?

  27. Yoda 在February 5, 2021 at 7:31 pm

    I’ve been waiting for a jaw dropping update since Propecia came out! in the mid-90’s!

  28. Woofy97 在February 6, 2021 at 3:02 pm

    I heard Bernstein medical and other hair transplant clinics in the United States are going to start offering hair banking and then sending it to the U.K hairclone until we get hair cloning. That’s what Dr Shaver said in a recent interview.

  29. Woofy97 在February 6, 2021 at 3:05 pm

    It’s cool to have hair banking but I’m not that excited Because it’s not really going to do anything. It’s just tease

    • DEE 在February 6, 2021 at 5:01 pm

      It’s good to have updates from admin but everything is a tease until we hear it everywhere on media we will know it has arrived been waiting 42 years so not holding my breadth have tried lots of teases then got transplant which has held me until the big one I hope

  30. KJ 在February 6, 2021 at 5:15 pm

    Hi Admin,
    Below is a link to a new method being used in Iran. Some clinics are doing it now. It seems intresting.

    • D1 在February 7, 2021 at 9:03 am

      @FollicleThought how good is your current pipeline of news?

      • 英格兰vs美国皇冠比分 在February 7, 2021 at 10:06 am

        Good enough D1. Every month there’s a chance for a development, we just have to be patient until it gets here.

    • KJ 在February 10, 2021 at 1:49 am

      Hi Admin,

      What do you think about this method? Is it a safe method? Also below is a video of this method and results:

      Thank you!

  31. Messi 在February 7, 2021 at 8:02 am

    你好管理员,do you think Samumed could be released this year and what’s the news on follicabio and breezula?
    Thank you

    • 英格兰vs美国皇冠比分 在February 7, 2021 at 10:07 am

      I suppose it’s possible in Turkey Messi. There’s no news on Follica, they are either preparing for their clinical trial or have stalled their plans. Breezula is preparing for a phase 3 trial.

      • Messi 在February 8, 2021 at 6:38 am

        Do you think samumed would be a good drug admin? and disappointed about follica, but well let’s hope for the best
        Thank you

  32. Twenti 在February 7, 2021 at 4:30 pm

    Admin have you been in touch with J.Hewitt/Tissuse recently? A update from them would be nice.

    • 英格兰vs美国皇冠比分 在February 7, 2021 at 5:36 pm

      I do keep in contact with J Hewitt but at the moment there is nothing new to report on.

      • Twenti 在February 8, 2021 at 7:26 am

        Thanks for the update. I hope they have some positive news to share by the end of the year.

  33. shaz 在February 8, 2021 at 1:43 am

    would this drop the sensitivity to androgens on all hairs and potentially grow back hairs that have gone away since the potential to grow is still there but the dht is killing them off?

  34. Vienna Austria 在February 8, 2021 at 10:41 am

    @Ben: Sadly, I didn’t manage to participate but as it seems it was for potential investors only as Stemson is apparently going through the process of raising further funds for the upcoming pre-clinical studies.

    On another note, some of you may read it already but Riken has set up a Twitter account solely for the hair tooth organ regeneration segment on which they posted: “The novel study on the relation to clinical application of hair follicle regeneration will open at 10 AM (UK time) February 10, 2021. Coming soon.” Honestly speaking, the Twitter account does not seem to be the most reliable source but this could potentially be the first sign of life of the project in quite a while. Not getting my hopes up there either but after H2 2020 I guess any news is good news.

    • 英格兰vs美国皇冠比分 在February 8, 2021 at 12:40 pm

      Yes, I saw this too, Vienna and was going to try to surprise everyone (if the account is legitimate) but we shall see!

      • Vienna Austria 在February 8, 2021 at 2:53 pm

        Sorry, admin – I didn’t want to spoil the surprise! As you said, I’m also not quite sure how legitimate the account is and additionally I’m not entirely sure of how to interpret the quote I posted above. If all goes well, we’ll know by Wednesday. Fingers crossed!

  35. Vienna Austria 在February 8, 2021 at 11:56 am

    RepliCel also published some info on RCH-01 and their relationship with Shiseido today:

  36. GG 在February 8, 2021 at 12:30 pm

    Hello guys,
    GG is here. I’d like to ask what are your best bets. From which companies are you expecting the news – It’s done!
    And what do you think about the theory, companies working in shadow on the solution. I guess, big pharmaceutical companies should have some RND for that ??♂️

    P.S. I amazing how this community support each other. All the best to you guys ??

  37. Woofy97 在February 8, 2021 at 3:50 pm

    This is exciting to hear about the tsuji news and an update on the 10th but Im not going to hold my breath because it could be a fake account. So that’s my thought

  38. steve 在February 8, 2021 at 4:16 pm

    they posted about the twitter account on the riken website. I think its legit. in any case we will see in just two days

    • 英格兰vs美国皇冠比分 在February 8, 2021 at 7:08 pm

      Yes, it’s true the Riken website now mentions that the Twitter account is legitimate.

  39. woofy97 在February 8, 2021 at 6:31 pm

    i feel like the researchers at riken are reading our comments lol because the other day i said i wanted to see a jaw dropping update, (maybe this will be?). maybe its just a coincidence but idk

    • Twenti 在February 9, 2021 at 3:38 pm

      Lol, it’s probably just a coincidence but 2021 could turn out to be a good year after all.

  40. Vienna Austria 在February 9, 2021 at 7:02 am

    They posted again on their Twitter account: “Thank you for your collaboration with and encouragement to our work. We finished a Press Conference participated with major Japanese media. Please watch the news of #hair_follicle_regeneration. Embargo time is 10 AM (UK time) February 10th.”

    I mean, the way they are building suspense here (“embargo time”) is making me curios.. I just hope they don’t announce they are going down the topical road with something that’s 5% more effective than Minox which Dr. Tsuji coincidentally found while doing research on cloning. Tomorrow could be a big day for the hairloss world, we’ll find out soon!

    • OceanMountainSky 在February 9, 2021 at 10:56 am

      @Vienna Austria – I’d take that slightly more effective than minox solution and I’d be ecstatic tbh.

      • Vienna Austria 在February 9, 2021 at 11:08 am

        Yes, Ocean – you are probably right. It’s just the way they are posting on their Twitter account, which makes it look like there’s really big news coming towards us tomorrow. However, I’d also be happy with an improved Minox. It’s probably best, no matter how much they tease, to keep expectations low.

      • Yoda 在February 9, 2021 at 6:43 pm

        I’m with you Mountain Sky, especially if it was going to be released soon…which anything in regards to hair cloning won’t be on the market in the near-term. (Yoda’s opinion, not fact).

  41. itiswhatitis 在February 9, 2021 at 8:19 pm

    when tsuji starts the studies, the rest will also go much faster. Stemson will come under pressure.

    • Woofy97 在February 9, 2021 at 9:34 pm

      Itiswhatitis yeah I was thinking that earlier today.

  42. Soul 在February 9, 2021 at 10:25 pm

    It would be good to remain cautious until we see what it is. This way we avoid crying, cursing, etc. and having to read people’s emotional states.

  43. Woofy97 在February 10, 2021 at 5:35 am

    I was hoping for a human picture of hair cloning result and they post a mouse with hair oh my god what a surprise ?. I’m disappointed.

    • al.budny 在February 10, 2021 at 5:57 am

      so nothing new about Tsuji?

    • Sonic 在February 10, 2021 at 6:20 am

      对粗直浓密的,我们看到老鼠的头发的照片years ago by other companies, really nothing new wit Tsuji.
      Because what happens in mice doesn’t always happen in humans.

      Tsuji still needs to provide us with physical proof of something in humans.

      I’m also expecting something more from Tsuji besides something slightly better than Minoxidil. I mean, there’s treatments in the pipeline that will be released sooner that are already claiming to have better results than Minoxidil, even TH16 claims to be better than Minoxidil and that’s a natural topical lol which is going to be released in Q1 this year!

      People would expect the highly regarded Tsuji, who people widely regard as one the the biggest names in the hair loss restoration game, to blow these smaller companies out of the water with their technology and treatments for hairloss.

      Someone regarded in such high esteem by the hairloss industry such as Tsuji should be releasing treatments FAR more effective than the others. He shouldn’t be planning on releasing small things the equivalent of some of the smallest companies in the pipeline.

      We’ll see soon enough if he really is worth the hype or if his just overrated.

      • al.budny 在February 10, 2021 at 6:23 am

        Sonic so no human trials anytime soon?

  44. Woofy97 在February 10, 2021 at 5:39 am

    And I’m pretty tsuji said like 5 years ago they figured out the cycling issue.

  45. Dimitri on April 15, 2021 at 4:17 pm

    Wasn’t Kintors phase 2 hair loss clinical trials results suppose to be posted in March? Or am I wrong?

    • 英格兰vs美国皇冠比分 on April 15, 2021 at 6:58 pm

      I don’t believe so Dimitri, Follicum is having results around this time.

  46. jason on April 26, 2021 at 4:25 pm

    these drugs are cool but i dont see how they improve upon current solutions like accutane or minoxidil. they may have less side affects but their benefits are limited to the local tissues theyre applied to.

    acne vulgaris affects the entire surface area of your body, with the worst of it affecting your face and scalp where our sabacus glands are most abundant. youd hav to prescribe one topical for your body, another for your face, then another for your scalp just to meet the effectiveness that a systemic drug like accutane could give you with single pill a day.

    same for hair loss, topical min is a joke compared to taking it orally. which is why the first line of defence against hair loss is most countries is a daily combo of .5mg oral dutasteride with 10mg oral minoxidil. i hope this issue gets addressed before they hit markets.

  47. Baumer on July 13, 2021 at 12:38 pm

    Help us, Kintor Pharmaceuticals, you’re our only hope.

  48. 英格兰vs美国皇冠比分 on July 13, 2021 at 11:40 pm

    I think this news was so similar to Sunday’s that most people don’t realize it’s a different article.

  49. Baumer on July 14, 2021 at 4:29 am

    ^Agreed, maybe it would make more sense to combine the two articles? My response to this news is also the same: Kintor seems amazing, I am concerned about side effects. The press release statements seem to contain somewhat contradictor descriptives: “devoid of” and “mitigate” carry very different implications.

    • 英格兰vs美国皇冠比分 on July 14, 2021 at 9:19 am

      It’s a good idea but the reason there were 2 articles in the first place was because Kintor has 2 drugs at the moment. I don’t favor the idea of a large number of updates in any article, so will keep it the same for now. Soon enough Kintor will have better news and I will publish a brand new article for it.

      Also, I’m interested to see how much GT20029 can mitigate side effects. They talk about only needing a small amount to be effective.

  50. Yoda on July 14, 2021 at 6:37 pm

    Have to admit, Yoda didn’t realize it was two different articles on two different drugs from Kintor, with similar clinical trial news. Hard to keep this all straight, which is actually a good thing. Many irons in the fire, thanks Admin!

  51. Sonic on September 14, 2021 at 6:10 am


    I found something quite interesting.

    There’s a company called ARVINAS which is already developing a PROTAC Androgen Receptor Degrader which is already in Phase 2 Clinical Trials for their drug called ARV-110

    The only thing that I find highly strange is that it is only being trialed for Prostate Cancer by the company.

    We know that Anti-Androgen treatment is often used for Prostate Cancer treatment just like Finasteride is used alternatively.

    So my question is, do you think ARVINAS does not know about the Golden opportunity they have that this treatment can also be used as the solution for Androgenetic Alopecia ?!

    Do you think you could please reach out to ARVINAS and find out if they could start a trial for AGA? And if they know this PROTAC can also work for Male Patterned Balding, which from a business point of view for them, would mean killing 2 birds with one stone and obtaining double the amount of profits by treating 2 problems! (Hairloss and Prostate Cancer)

    It would be amazing because they might be able to actually release their PROTAC well before even Kintor Pharmaceuticals GT20029, since they have already finished their Phase 1 and soon their Phase 2 Clinical Trials!

    Its definitely worth a shot.

    • 英格兰vs美国皇冠比分 on September 14, 2021 at 12:19 pm

      I do think they know Sonic and have contacted their founder a long time ago. I will try again for fun since you’ve brought it up today.

      • Sonic on September 15, 2021 at 7:57 am

        Thank you very much admin. I really appreciate it. Really hope we get good news. It’s too much of a great opportunity for them as well to pass up, it wouldn’t make sense if they chose not to.

  52. 罗素 on October 4, 2021 at 2:34 am

    This seems to say that Kintor’s new anti-androgen (GT20029) works topically and literally ZERO of the drug gets deeper than the local skin where it is applied so literally zero of GT20029 gets into the body. Is that correct? Could you please ask them about that because if literally zero of this drug gets deeper into the body then there is a zero percent chance of side effects.

    • 英格兰vs美国皇冠比分 on October 4, 2021 at 10:22 am

      罗素, I think zero is unlikely, it’s more likely that a negligible amount gets into the body which could drastically reduce the potential of side effects and would be a big win for almost everyone.

    • Arias on November 21, 2021 at 9:37 am

      Russel, ZERO is impossible, it will never be. Even drinking too much water has side effects! Your body is programmed to work so that your hair falls out at a certain point. Fighting this is, by and large, an alteration of this. Now this all is about finding the right way to do it with the minimum possible sides.

      There will always be someone who can’t tolerate the treatment, someone who experiences little to no improvements and so on. That’s why is so important to widen the range of options to fight hair loss: if a treatment is not good for you, another may be. So far we have extremely limited cards to play…

      • Josh 在February 4, 2022 at 1:12 pm

        Arias—spot on Arias. Always see sensible comments from you and they seem to coming from a good place as well. What is your current situation and regimen if I might ask. No need to answer me if you like to keep some things private. Thanks!

  53. Ali on January 5, 2022 at 5:31 am

    When phase 1 trail of GT20029 is expected to complete?
    usually, what is the duration of phase 1 , 2 and 3 trails?
    will GT20029 cure the hair loss permanently? or will it have to keep using for life time as similar as other topical drugs?

    • 英格兰vs美国皇冠比分 on January 5, 2022 at 4:46 pm

      Durations of phase 1 trials are usually within 4 months. Kintor could have already wrapped their phase 1 of GT20029 and is observing data and/or potentially doing follow up evaluations on subjects to ensure further safety.

  54. Shery 在February 3, 2022 at 12:10 pm

    Thanks alot admin for let us know about these news.

  55. skyecheeseburger 在February 3, 2022 at 1:37 pm

    Good to see good news rolling into February. Hope this keeps up

  56. Nick 在February 3, 2022 at 5:12 pm

    @Admin, are you aware that for their other product Phase III clinical trials have started in China?

    • 英格兰vs美国皇冠比分 在February 3, 2022 at 6:50 pm

      Yes Nick, thanks. If in doubt please check the Updates page. I typically suggest people to bookmark the page and check it out a few times a week in order to stay up to date on the latest happenings Other pages like the Ultimate Guide may take a sec to get updated.

  57. just a bald guy in bed on his phone 在February 3, 2022 at 7:24 pm

    pardon my language admin … but holy fucking shit

    2022 is starting off with a blast ! the time is coming

    • 英格兰vs美国皇冠比分 在February 3, 2022 at 7:28 pm

  58. Big Kahuna 在February 4, 2022 at 2:51 am

    Thanks for the update FT 2022 is already shaping up to be a promising year

  59. Shayak 在February 4, 2022 at 6:55 am

    Thank you for the update admin. What the hell is happening , i don’t want this dream to end.

  60. MasterV 在February 4, 2022 at 11:53 am

    Hello FT,

    Man you are on a roll with news! Keep it coming This curse needs to be brought to an end lol thanks for the update

  61. Zero fin 在February 4, 2022 at 2:16 pm

    Calm down guys we still don’t have news on an oral medication that regrows 100,000 follicles on your head until than I won’t be satisfied. Kantor won’t give you a full head of hair.

  62. Josh 在February 4, 2022 at 3:15 pm

    Zero fin—if that’s seriously the only thing that would satisfy you, then you might as well leave this website. Also, any progress should be appreciated, pay some respect to the admin and the researchers actually working on AGA. Nobody is benefiting from your useless comment.

    • blave 在February 4, 2022 at 3:24 pm

      Progress is great but people who already lost all their hair and want them back are obviously not too interested in new maintenance drugs. I understand this sentiment. Fortunately, new maintenance drugs will come very soon, stronger growth stimulants probably too,
      and for many guys, this is fantastic news. Turning a Norwood 7 to a Norwood 0 is just possible by hair multiplication, but there are so many question marks. Will it cycle? Will it be safe? This is actually very important because the fda sees baldness as a cosmetic problem and will be very very strict on safety. Will it be dht-resistant? Can they control color? Can they control thickness? Curl? It will take a while to address all these questions.

  63. Zero fin 在February 4, 2022 at 4:07 pm

    Pay some respect to the researchers? Pff that are taking so fucking slow I’ll pay them respect when they actually get the job done! Josh you must be new

    • blave 在February 4, 2022 at 4:39 pm

      Zero fin bro chill. A cure won’t come this decade. Find a way to deal with it now.

  64. Mr Burns 在February 4, 2022 at 4:33 pm

    Chill brothers, chill out. We are all in the same boat. Even with the available treatments like hair transplants you don’t have to be bald. There’s always SOMETHING you can do. Even if you can’t go from NW7 to a perfect Norwood 0 you can still have hair. No need to lash out. We’re all going through the same thing.

    • Josh 在February 4, 2022 at 5:45 pm

      Mr bums—Il chill out. I admit I was maybe a bit too personal there. Thanks for trying to mediate.

  65. Josh 在February 4, 2022 at 5:42 pm

    Zero fin—perhaps I was a bit harsh, but this crosses the line. I just feel that you are not respecting the admin with a comment like this. Not everyone is in the same boat and we’re all trying to benefit from the research. Now you might not be satisfied until you can have a magical pill that solves all your issues, but there are other people too who ARE happy with these developments.

    • Zero fin 在February 4, 2022 at 5:51 pm

      You were a bit harsh! I don’t care if my comments crossed the line you were rude in your comment! I respect admin that’s why I didn’t mention him when I was attacking the researchers.

      • 英格兰vs美国皇冠比分 在February 4, 2022 at 7:01 pm

        Ok guys, I brushed over the comments and removed one with a direct insult. Let’s drop it. Josh had good intentions with his comment and I appreciate it though it led to more back and forth. Please be respectful.

  66. Shayak 在February 5, 2022 at 6:46 am

    If Epibiotech / hairclone succeeds and their cells don’t loose inductivity and the treatment is deemed safe, cure could come within 2025. Even if the results are a 20% improvement on the intercytex results, multiple injection could in theory cure a NW5 easily.

    • Georg 在February 5, 2022 at 4:28 pm

      I see a lot of “ifs” here

  67. Dee 在February 5, 2022 at 4:40 pm

    thanks to follicle thought for bringing us all the news on the the latest developments ,it brings us hope, and ive been hoping for about 44 years now, and will continue to do so ,thanks again.

    • Josh 在February 6, 2022 at 7:41 am

      Dee—right Dee! And if we look at the last 44 years, quite some progress has been made. The hair transplants today are much much better than even 20 years ago. Also, finasteride and minox have been fantastic new medications. Now within the coming years, we might see the first FDA approved topical anti androgens as well.

  68. Big L 在February 6, 2022 at 10:42 am

    Does anyone know if pyrilutamide is going to block DHT and testosterone on the scalp like RU58841, or will it only inhibit DHT? And what about GT20029?

    • Shayak 在February 6, 2022 at 1:27 pm

      @BigL , none of the above. It competes with DHT for AR, and since its binding affinity is stronger than DHT (in theory) so it will bind with the AR hence DHT can’t bind with it.

  69. only21 在February 6, 2022 at 11:13 am

    Can someone who’s been tracking this industry for a long time give a more seasoned view of the current research? I’ve heard some people saying that they’re tired of hearing the cure is almost here for the past 20 years. Is this still the case? Is there anything truly groundbreaking that makes the prospect of hair loss treatment any better than it was 20 years ago?

    • 英格兰vs美国皇冠比分 2022年2月6日上午54所以

      Others can feel free to share, but the simple answer is that the number of companies with potential treatments (i.e. shots on goal) is significantly higher than anytime over the last 40 years. Not to mention that the understanding of hair follicle biology has improved to some degree. There’s something like 46 companies listed in the Master article and I’d say around 15-20 are near term contenders. The application of science improves over time, it’s a validated statement.

    • Arias 在February 7, 2022 at 10:27 am

      @only21 this “20-year stuff” is one of the dumbest memes around, fueled by trolls, incels and other people who have time to lose on hair loss forums online!

      There are a lot of treatments in clinical trials, nothing like this happened 20 years ago, you can verify that yourself by googling “hair loss clinical trials” and filtering the reseach before 2005 or 2006. Just a couple of interviews to random people promising stuff. Quite different than actual companies researching actual medications, as it is now!

      People writing “guh, SaMe ThInG 40 yEaRs AgO”…yeah man, except for minoxidil, finasteride, dutasteride, hair transplants, palmetto, LLLT, PRP, etc…

      • Josh 在February 7, 2022 at 1:40 pm

        Arias—agree with this so much. In fact, a comment like this is important to be repeated from time to time to snuff out these wasteful comments.

        edit: to be clear, I do not mean inquisitive questions like yours only21!

  70. blave 在February 7, 2022 at 7:59 am

    Obviously the admin knows much much more than me and has way better insights.
    I would say there was never that much research/attempts and the newest science is thrown at hair loss now. There will surely be effective topical anti-androgens out within 5 years complimenting the things we have now. Additionally, cell therapies are C
    currently being developed (like what hair clone is doing). I believe this might be offered within the next 5-10 years. Moreover I feel like hair transplant surgeons are really pushing the boundaries on what can be achieved with body hair, look up eugenix in India for extreme cases. Moreover, I feel like hair systems are losing their stigma amongst young people due to clever marketing by studios, at some point it won’t really have the toupee falling off joke from the 80s stigma anymore.
    The rest is speculation as nothing is in clinical trials today. Obviously hair cloning is the holy grail, but it is the hardest to figure out too.

  71. Woofy97 在February 7, 2022 at 1:05 pm

    Screw the years guys 20 years 5 years 10 years. Just ignore it

    • Yoyo 在February 7, 2022 at 4:44 pm

      Exactly woofy, nobody knows how long it will take let’s just pray these things come quickly

  72. Woofy97 在February 8, 2022 at 12:13 am

    I’d like to make a correction on a hair system comment I made like last week. I bashed mom and pop places but some I have found offer really good hair systems. It really depends on where you go.

  73. blave 在February 8, 2022 at 5:06 am

    damn I am sorry for throwing around with years, I agree this is random speculation which helps no one. Anyway, we have many, many companies developing stuff and this is for sure great.

    @Woofy97 may I ask you about your overall experience wearing a system? Do you think it increased your life quality? I am considering it as I think they look great, but I am asking myself about the psychological side sometimes, like do you feel like you’re “living a lie” or are you open about it in the firsr place? Thanks!

  74. Mark 在February 8, 2022 at 6:26 am

    According to Statnews, 1h ago, Biosplice – Former Samumed – fired 1/4 of their staff and stopped the work on their hairloss drug.

    Man i am running out of time and don’t want to destroy my hormones with Finast.

    Hopefully Kintor can have a successful launch of their stuff soon.

    • Georg 在February 8, 2022 at 3:55 pm

      I am running out of time too. I took fin 5 years. (Was pretty good) then i got greedy and took dut….. Now i am fked….

      Kintor is the only hope for me since id like to stop the hairloss in the next years.

    • Ret 在February 8, 2022 at 4:02 pm

      @Mark我感觉你,我准备争取hair, even condemning myself to a lifelong use of a topical solution whatsoever, undergo hair transplants, spend money and time…but that drug is not worth it imho…
      I respect who thinks otherwise

      • Sonic 2022年2月8日下午的地方

        @Ret I feel the exact same way as you. I ain’t going down without a fight. And it’s a complete no to fin for me as well.

  75. Woofy97 在February 8, 2022 at 2:48 pm

    Hi blave I don’t wear one but am really considering it. Not if it looks really natural I would try and not think that way if it makes you more confident it doesn’t matter.

  76. Woofy97 在February 8, 2022 at 4:15 pm

    This Canadian guy does really good work! The only negative thing I can say is I wish the camera quality was 4K and not 720 little suspicious lol but dang his work looks great! The hair is not puffy and looks very natural same with the hairline but I’d like to see the hairline in 4K!

    • Josh 在February 8, 2022 at 4:42 pm

      Woofy97–wow. Looks awesome. I mean, I’ve done a hairtransplant and Im a pretty dense Norwood 1,5 right now, but seeing that amazing hair system makes it tempting to shave it all off and just wear something like that haha.

      • Woofy97 在February 8, 2022 at 4:49 pm

        Hi josh Lol I know it’s looks so good. I’m about to look for flights to Canada lol

        • Josh 在February 8, 2022 at 5:22 pm

          Woofy97–haha, understandable. No shame in wearing one in my opinion. They give better results than any hairtransplant could ever give you and in the end it’s about what you wanna do with your looks. The amount of hate I’ve gotten for opting for a hairtransplant was also surprising..

  77. Joe Bloggs 在February 14, 2022 at 5:26 am

    Been wearing a hair system for 2 & a half months now. Been a few ups n downs but overall i will keep wearing. I actually wish i got it earlier..

    • Josh 在February 16, 2022 at 8:23 am

      Joe Bloggs–what were your ups and downs exactly Joe?

  78. […] link to the press release and bonus news about a pyrilutamide US phase 2 trial while the article is stickied to the […]

  79. Ralph Wiggum on August 23, 2023 at 6:44 pm

    Great news about GT20029, but why do you say that expectations around Pyrilutamide have likely decreased slightly? Have I missed an update?

    • 英格兰vs美国皇冠比分 on August 23, 2023 at 8:47 pm

      Ralph, I was referring to the difference in hair count increase from the Chinese trial to the US trial. I’d have to go back to recheck, but I think the numbers were like 22 in China to 10 in the US. No hyperbole in my statement, just stating that the expectations are a little different now. What’s your take?

      • Ralph Wiggum on August 24, 2023 at 8:59 am

        Thanks for replying, that makes sense. In that case you and I are pretty much on the same page. But I hope the combo of Pyrilutamide and Dutastaride helps me keep what I’ve got left until GT20029 is available.

  80. Andy on August 28, 2023 at 5:29 pm

    Did I read that correct that clinical trials could start as early as next year?

    • 英格兰vs美国皇冠比分 on August 28, 2023 at 9:33 pm

      Yes, that’s right Andy. I’ve been aware of this for several months when JW Pharma issued a press release for the granting of their patent in Russia. I’ve updated my original piece on the drug here:

      JW Pharmaceutical JW0061 Hair Regrowth Drug

      • YoYo on September 1, 2023 at 5:59 pm

        It’s a little disappointing that Epibiotech (Another S. Korean company) hasn’t mentioned anything about their clinical trials for EPI-001 considering they were meant to start in the 1st half this year. (I believe they are funded by the government too, unless I’m mistaken).

        • 英格兰vs美国皇冠比分 on September 2, 2023 at 10:07 am

          YoYo, I should have some commentary coming from Epibiotech this upcoming week.

          • YoYo on September 2, 2023 at 2:30 pm

            That’s great! I know you’re probably tired of hearing this but thanks so much for your hard work!

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